★★★★★ (1,276) 13,000+ Active Users

Defend — Saw Palmetto Complex

Take 2 daily · 60 capsules

A daily supplement featuring Saw Palmetto, Beta-Sitosterol and other research-backed ingredients that support healthy hair from the inside out.

Regulates DHT — the hormone that accelerates hair loss
Supports nutrient partitioning to the scalp
Research-based, natural ingredients
Choose Your Supply:
Made in USA3rd-Party Tested150-Day Money-Back
1

Take two (2) capsules daily with food.

Please note: Consistent use is key — this is a daily routine.

Defend is led by clinically-dosed Saw Palmetto and Beta-Sitosterol, supported by other naturally occurring, research-backed ingredients.

See the actives in our formula:

Saw Palmetto Berry Extract — 300 mg

Saw palmetto is a well-studied botanical, traditionally used to support normal hair and scalp health.

Plant Sterol Complex — 100 mg

38–45% beta-sitosterol. Naturally occurring plant compounds studied for supporting healthy hormonal balance and DHT regulation.

Stinging Nettle Root Extract — 100 mg

A traditional botanical that supports healthy DHT levels by reducing the binding of testosterone to SHBG. Works synergistically with saw palmetto.

Catalase Complex — 50 mg

An antioxidant enzyme that helps neutralize hydrogen peroxide buildup in the follicle — linked in research to premature graying and follicle stress.

Phase One Block

Saw Palmetto and Beta-Sitosterol get to work alongside supporting nutrients that help maintain a calm, healthy scalp environment.

Phase Two Stabilize

Hair texture and feel improve; existing strands feel more anchored. Antioxidant-rich plant sterols help keep the scalp environment stable.

Phase Three Sustain

DHT activity at the follicle stays consistently low. Existing hair holds and thickens, and the scalp conditions for sustained healthy growth are locked in. Continued daily use compounds the protective effect over the long run.

13,000+
Active Users
4.8 ★
From 1,276 Reviews
USA
Made & Formulated in the USA
150 Day
Money Back Guarantee
Defend — Saw Palmetto Complex
$49.00
The Actives

Studied. Sourced. Stacked.

Every ingredient in Defend is dosed at levels referenced in peer-reviewed clinical literature. No proprietary blends, no fairy dust.

01
Saw Palmetto Extract
Saw Palmetto Extract
300 mg · Oral · DHT Modulation

A plant-derived extract studied for its role in supporting healthy DHT activity. The no-prescription DHT pathway, taken once daily.

02
Plant Sterol Complex
Plant Sterol Complex
100 mg · Oral · Hormonal Support

Naturally occurring plant compounds studied for their role in supporting healthy hormonal balance. Works synergistically with saw palmetto.

03
Stinging Nettle Root
Stinging Nettle Root
100 mg · Oral · SHBG Support

A traditional botanical that helps modulate the binding of testosterone to SHBG, supporting healthy DHT activity at the follicle.

04
Catalase Complex
Catalase Complex
50 mg · Oral · Antioxidant

An enzyme that neutralizes hydrogen peroxide buildup in the follicle — research links accumulated peroxide to follicle stress and graying.

A Modern
Epidemic.

Our forefathers had double the amount of hair we do. Stress, poor sleep, processed diets, and toxins are destroying our endocrine systems and our overall health.

The impact? Low sex drive, hair loss, and mental health issues — making it harder to perform at your best in life.

The good news: Maneup Labs helps you reclaim your edge with our peptide-powered scalp care system.

NORMAL RANGE 80 60 40 20 % MEN WITH PATTERN BALDNESS 20 30 40 50 60 70 80 AGE WITH MANEUP LABS Maneup Restore serum
Maneup Defend
Defend, Decoded

What is it?

Defend is a daily supplement featuring clinically-dosed Saw Palmetto and supporting nutrients that work from the inside out — no prescription, no hormones.

  • Natural DHT defense Saw Palmetto and Beta-Sitosterol are plant compounds studied for their role in supporting normal hair and scalp health. No hormones in the formula.
  • Supports normal hair and scalp health Supports healthy DHT balance at the scalp while supplying the building blocks your scalp needs for healthy hair.
  • 3rd-party tested · Made in USA Every batch verified for potency and purity. Formulated and bottled in FDA-registered facilities.
Two pathways. One capsule.

How does it work?

Maneup Defend capsules
01

Support the scalp from the inside.

Plant-derived ingredients — Saw Palmetto and Beta-Sitosterol — are studied for their role in supporting the scalp environment. No hormones in the formula.

02

Prime the scalp for growth.

Supporting nutrients — Stinging Nettle, Catalase Complex, Plant Sterols and key vitamins — promote hair growth, reduce stress and inflammation, and prime your scalp environment for thicker, healthier hair.

03

Sustain the result.

Defend works cumulatively — every day you take it, DHT activity at the follicle stays modulated and your scalp keeps the conditions hair needs to hold and grow. No on-off cycles, no rebound.

The Guarantee

Try Defend for 150 days. Not satisfied? Full refund.

Try Defend for 5 months. If you're not satisfied, we refund you in full. No return, no questions.

Start Your Protocol

Easily change, pause or cancel anytime

Try Defend for 150 days. Not satisfied? Full refund.
The Category, In One Glance

The Maneup Labs Difference.

Maneup
Other Brands
Botanical actives at clinical dose
Stinging nettle + catalase synergy
No hormones in the formula
Made and tested in the USA
150-day money-back guarantee

Frequently Asked Questions

How is Defend different from other approaches?
Defend is a daily supplement built around saw palmetto and plant sterols — plant compounds studied for their role in supporting normal hair and scalp health. It is taken orally, contains no hormones, and needs no prescription.
When will I see results?
Many users report changes over the first couple of months. Defend is the daily supplement layer of the routine. To add a topical, pair it with our Restore copper peptide serum.
Can I take it with Restore?
Yes — that's our Restore Max stack. The serum addresses follicle signaling topically, the capsules address DHT pressure systemically. They work on different pathways and stack cleanly.
Are there side effects?
Defend is well-tolerated in published research. Some users report mild GI discomfort in the first week if taken on an empty stomach — always take with food. No libido or hormonal side effects reported in our customer base.
Can I take it with other medications?
Do not take Defend within one hour of any prescription medication. If you're on dutasteride or any hormone-modulating drug, consult your prescribing doctor before adding Defend.
What if it doesn't work for me?
You have 150 days. If you're not satisfied by month 5, email hello@maneuplabs.com and we'll refund you in full. No return, no questions.
How does the subscription work?
Choose 1, 2, or 3-month supply. Subscribe & Save gives you 10% off plus automatic refills. Pause, skip, or cancel anytime from your account.
Real Reviews

Defend customers.

★★★★★ 1,276 verified reviewsLeave a review